Fig. 2

Resistant allele RAW 264.7 transfectants generate enhanced RB responses, which are not extinguished following LPS stimulation

PMA-elicited RB was measured in resting (a and c) or LPS-treated (b and d) resistant and susceptible transfectants at 24 (a and b) or 30 (c and d) hr after LPS (25 ng/ml). Results are expressed as a ratio of formazan: crystal violet readings from six wells/treatment. Asterisks indicate significance levels (*p < 0.05; **p < 0.01; ***p < 0.001) for results of Student’s t tests used to compare each resistant transfectant against the susceptible transfectant 30S. Similar levels of significance were observed for comparisons with 10S and 25S. Results are representative of five independent experiments performed.