Fig. 6From: Nramp Transfection Transfers Ity/Lsh/Bcg-Related Pleiotropic Effects on Macrophage Activation: Influence on Oxidative Burst and Nitric Oxide Pathways Inhibition of mitochondrial electron transport suppresses RB in RAW 264.7 transfectant macrophages Resistant allele transfectant clone 7.5R was used for inhibition studies with the complex I inhibitor rotenone (a) and the complex II inhibitor thenoyltrifluoroacetone (b). Control (filled) and activated cells (open) exhibited a dose-dependent decrease in ROI production with both drugs.Back to article page