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Fig. 6 | Molecular Medicine

Fig. 6

From: Nramp Transfection Transfers Ity/Lsh/Bcg-Related Pleiotropic Effects on Macrophage Activation: Influence on Oxidative Burst and Nitric Oxide Pathways

Fig. 6

Inhibition of mitochondrial electron transport suppresses RB in RAW 264.7 transfectant macrophages

Resistant allele transfectant clone 7.5R was used for inhibition studies with the complex I inhibitor rotenone (a) and the complex II inhibitor thenoyltrifluoroacetone (b). Control (filled) and activated cells (open) exhibited a dose-dependent decrease in ROI production with both drugs.

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