Oligoclonality in the Human CD8+ T Cell Repertoire in Normal Subjects and Monozygotic Twins: Implications for Studies of Infectious and Autoimmune Diseases

Table 3 MZ twin sets used for study and the corresponding TCRBV segments in which CD8 ⁺ oligoclonality was observed

Twin	Member	Age (years)	Status	CD8 Oligoclonality in TCRBV
1	An	51	RA	9, 11, 15, 16
1	As	51	Normal	1, 5S1, 8, 11, 17, 24
2	A	17	Normal	4, 14
2	M	17	Normal	14
3	Da	14	Normal	5S2, 7, 12, 13S2, 16
3	De	14	Normal	5S2
4	F	15	Normal	2, 4
4	V	15	Normal	—
5	J	21	Normal	2^a
5	K	21	Normal	2, 18
6	M	29	SLE	8, 13S1
6	P	29	Normal	8, 13S2, 19

^aThe dominant band contained <50% counts but clonality was confirmed following sequencing.

ISSN: 1528-3658