Skip to main content

Table 2 Median values for expression of overrepresented TCR V β gene segments in CD4 + and CD8 + T cells from Myasthenia gravis patients ( n = 8)

From: Overexpression of Select T Cell Receptor Vβ Gene Families within CD4+ and CD8+ T Cell Subsets of Myasthenia Gravis Patients: A Role for Superantigen(s)?

 

Relative Vβ Gene Segment Expression in T Cell Subsets

Vβs

CD4+

p Valuea

CD8+

p Valuea

1

5.2 (2.2–5.8)b

<0.05

6.7 (6.0–14.7)b

<0.005

13.2

5.0 (4.4–8.2)

<0.05

5.5 (3.8–7.9)

<0.05

17

4.8 (3.1–6.4)

<0.05

4.2 (1.9–5.9)

<0.05

20

4.6 (3.0–6.6)

<0.05

4.9 (3.9–8.0)

<0.05

  1. aThe nonparametric Wilcoxon-Mann-Whitney two–tailed test was used to determine p values for comparison of MG patients and healthy controls regarding relative expression of the Vβs in CD4+ and CD8+ T cells.
  2. bNumbers in parentheses indicate the range (min–max) of values.