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Fig. 1 | Molecular Medicine

Fig. 1

From: Abnormal Activation of Glial Cells in the Brains of Prion Protein-deficient Mice Ectopically Expressing Prion Protein-like Protein, PrPLP/Dpl

Fig. 1

Glia-specific genes in the forebrain and cerebellum are upregulated in aged Ngsk Prnp0/0 mice. 10 µg of total RNA extracted from the pooled brain tissues of 102-week-old Ngsk Prnp0/0 and Prnp+/+ mice were subjected to Northern blotting using appropriate probes. The GFAP, LM, and IP3R1 probes were used in (a) and synaptophysin (Syn), MBP, and PLP probes in (b). The integrity and quantity of RNA were verified with a glyceraldehydes-3-phosphate dehydrogenase (GAPDH) probe on the same membrane.

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Molecular Medicine

ISSN: 1528-3658