Table 1 Expression of neuron-specific and prostate epithelial-specific proteins by C4-2b neuroendocrine-like cells
Treatment | PSA | Chromogranin A | Neuron Specific Enolase |
|---|---|---|---|
Control | 13.6 ± 2.4 | 222.8 ± 20.9 | 139.3 ± 22.8 |
NS-398 | 25.6 ± 1.3 | 732.8 ± 48.8 | 700.8 ± 49.8 |
Cells were collected following 72 h treatment with 10 µM NS-398 as described in Materials and Methods. Total cellular lysate was used to determine PSA, Chromogranin A and neuron-specific enolase by ELISA. ELISA data are expressed as mean ng/ml total cellular lysate/105 cells ± SE of means. Data represents three separate experiments performed in triplicate. | |||