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Fig. 4 | Molecular Medicine

Fig. 4

From: Tumor-targeting, Systemically Delivered Antisense HER-2 Chemosensitizes Human Breast Cancer Xenografts Irrespective of HER-2 Levels

Fig. 4

Stability of AS HER-2 ODN in complex with F-Lip-2 in blood. Unlabeled ODN alone or ODN in complex with F-Lip-2 were intravenously administered once to mice. Blood was taken at various times from 30 min to 24 hr. The ODN from plasma was extracted, postlabeled with [γ-32P] ATP and separated on 19% polyacrylamide/urea gel. Lane 1 (control ODN), pure [32P]-labeled ODN run as a size standard. Lane 2 (plasma control), plasma from an untreated mouse.

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