Fig. 8From: Ubiquitous Induction of p53 in Tumor Cells by Antisense Inhibition of MDM2 Expression Effects of proteasome inhibitor MG132 on p53 and MDM2 levels. Cells were treated with 10 µM MG132 for 3 or 6 hr. Identical amounts of total cellular protein were fractionated by SDS-PAGE and analyzed by Western blot with monoclonal antibody 3G9 for MDM2 levels, and DO-1 for p53 levels.Back to article page