Molecular Medicine

Table 3 Correlation of serum miRNAs, APRIL and clinicopathological data in RA patients

From: Serum a proliferation-inducing ligand and MicroRNA-223 are associated with rheumatoid arthritis: diagnostic and prognostic implications

		APRIL	miR-223	miR-155
APRIL	r		0.29	−0.05
APRIL	P		0.038*	0.76
miR-223	r	0.29		0.391
miR-223	P	0.038*		0.003*
miR-155	r	−0.05	0.391
miR-155	P	0.76	0.003*
ESR	r	0.17	0.023	0.03
ESR	P	0.27	0.88	0.87
RF	r	0.002	−0.18	0.19
RF	P	0.98	0.26	0.22
ANA	r	−0.04	− 0.19	− 0.43
ANA	P	0.79	0.23	0.005*
VAS	r	0.23	0.05	−0.1
VAS	P	0.06	0.76	0.55
DAS28-CRP	r	0.27	0.045	−0.02
DAS28-CRP	P	0.02*	0.78	0.89
TJC	r	0.2	0.03	0.05
TJC	P	0.16	0.85	0.75
SJC	r	0.18	0.15	0.053
SJC	P	0.25	0.33	0.74
Disease duration	r	−0.07	−0.12	0.02
Disease duration	P	0.65	0.42	0.90
MS by min	r	0.12	0.07	0.05
MS by min	P	0.42	0.63	0.75
Arthritis	r	0.05	−0.14	0.03
Arthritis	P	0.75	0.37	0.85
Deformities	r	0.08	0.04	−0.05
Deformities	P	0.6	0.82	0.77
Fever	r	0.23	0.23	−0.12
Fever	P	0.17	0.17	0.44
Subcutaneous nodules	r	0.005	0.39	0.21
Subcutaneous nodules	P	0.97	0.02*	0.19
Extra articular	r	0.19	0.12	−0.03
manifestations	P	0.22	0.44	0.86

r = spearman rho coefficient, correlations were done using Spearman correlation
*indicates statistical significance, P < 0.05. Correlations were done in RA patients with considerable disease activity (DAS-28-CRP ≥ 2.3), n = 72. ANA antinuclear antibody, DAS28 28-Joint disease activity score, ESR erythrocyte sedimentation rate, MS morning stiffness, RF rheumatoid factor, SJC swollen joint count, TJC tender joint count, VAS visual analogue scale for general health. Categorical data was considered zero (for absent) or 1 (for present) in the correlation

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ISSN: 1528-3658

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