From: The MC4R SNPs, their haplotypes and gene-environment interactions on the risk of obesity
Parameter | Control | Obesity | t (x2) | P |
---|---|---|---|---|
Number | 978 | 858 | Â | Â |
Age (years)a | 55.38 ± 15.33 | 56.29 ± 14.25 | −1.323 | 0.186 |
Body mass index (kgm2) | 20.01 ± 1.48 | 27.62 ± 3.07 | −66.13 | <  0.001 |
Waist circumference (cm) | 71.51 ± 6.487 | 87.52 ± 8.14 | −46.264 | <  0.001 |
Systolic blood pressure (mmHg) | 131.49 ± 23.28 | 137.83 ± 22.79 | −5.88 | <  0.001 |
Diastolic blood pressure (mmHg) | 80.64 ± 12.36 | 85.57 ± 13.67 | −8.063 | <  0.001 |
Glucose (mmol/L) | 6.17 ± 1.37 | 6.24 ± 1.32 | −1.283 | 0.200 |
TC (mmol/L) | 4.89 ± 0.98 | 5.09 ± 0.93 | −4.607 | <  0.001 |
TG (mmol/L)b | 1.17 (0.93) | 1.63 (1.22) | −14.095 | <  0.001 |
HDL-C (mmol/L) | 1.30 ± 0.29 | 1.25 ± 0.26 | 3.792 | <  0.001 |
LDL-C (mmol/L) | 3.10 ± 0.45 | 3.18 ± 0.50 | −3.695 | <  0.001 |
Male/femalec | 450/528 | 395/463 | 0.000 | 0.991 |
Smoking status [n (%)] | ||||
 Non-smoker | 772 (78.9) | 637 (74.2) |  |  |
 Smoker | 206 (21.1) | 221 (25.8) | 5.643 | 0.018 |
Alcohol consumption [n (%)] | ||||
 Non-drinker | 795 (81.3) | 686 (80.0) |  |  |
 Drinker | 183 (18.7) | 172 (20.0) | 0.522 | 0.470 |