Fig. 9

Immunohistochemical staining for human lamin B1 and CD73 at 8 weeks after implantation of hADSC disc on rat livers. A Implantation of disc alone without hADSCs. Staining for lamin B1 was completely absent. B Positive staining for human lamin B1, a characteristic highly conserved marker to demonstrate that the cells are human origin (arrows). C Implantation of disc alone without hADSCs. Since CD73 is expressed on subsets of T and B lymphocytes, biliary epithelial cells, and sinusoidal endothelial cells, there was focalized moderate staining for CD73 in the hepatic parenchyma. D Adipose-derived stem cells were stained positive for CD73 (arrows)