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Fig. 7 | Molecular Medicine

Fig. 7

From: CD44 promotes angiogenesis in myocardial infarction through regulating plasma exosome uptake and further enhancing FGFR2 signaling transduction

Fig. 7

Schematic diagram of the proangiogenic mechanisms of CD44 in MI. CD44 mediates the activation of the proangiogenic FGFR2 signaling pathway in endothelial cells and regulates the CAV1-dependent uptake of plasma exosomes, of which the contents miR-125b-5p and miR-223-3p enhance the FGFR2 signaling pathway to promote angiogenesis post-MI

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