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Fig. 4 | Molecular Medicine

Fig. 4

From: Small noncoding RNAs and sperm nuclear basic proteins reflect the environmental impact on germ cells

Fig. 4

Characterization of other small non-coding RNAs in sperm cells from the two study groups. A Pie charts representing the percentage of raw reads mapping on different sncRNA biotypes in the two residential areas. B Volcano plot of the log2FC and p-value of the 18 DE sncRNAs between LF and VSL samples. The color of the dots represents the sncRNAs log2FC, while the size is proportional to the p-value of the analysis. Dashed red line indicates the p-value threshold of 0.05. C Heatmap of the Z-score-normalized levels of the nine differentially expressed piRNAs in the comparison between LF and VSL samples. D Heatmap of Spearman’s correlation coefficients (Rho) computed between the nine differentially expressed piRNAs and spermiogram parameters, SNBP properties, and trace metals parameters (*p < 0.05)

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