Fig. 3From: Sirtuins in intervertebral disc degeneration: current understandingAnti-inflammatory effects of SIRT in IVDD.SIRT1 and SIRT6 mainly exert anti-inflammatory effects in IVDD.SIRT1 and SIRT6 can inhibit the NF-κB signaling pathway as well as the release of inflammatory factors through various pathways to exert anti-inflammatory effectsBack to article page