Figure 1From: Disease-Associated Prion Protein Elicits Immunoglobulin M Responses In VivoAdsorption of PrPSc is proportional to ICSM 35 concentration. Decreasing 10-fold dilutions of ICSM 35 (starting at 50 mg/mL) were adsorbed to Dynabeads as described in Materials and Methods. Next 107 of these beads were added to 50 µL ofa 10% RML brain homogenate spiked into an equal volume of 10% Prn-Po/o brain homogenate. Representative of 3 experiments.Back to article page