Figure 3From: Disease-Associated Prion Protein Elicits Immunoglobulin M Responses In VivoPolyclonal antibody responses to bead-adsorbed prion proteins including normal (●) and RML (▲) brain homogenates, and rPrP (■) in FVB-N Prn-Po/o mice (n = 3). Several specificity controls were used including omitting the homogenate/antigen (♦), adsorbing antigens from Prn-Po/o mice (▽), or using an irrelevant isotype-matched mAb control for adsorption.Back to article page