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Figure 6 | Molecular Medicine

Figure 6

From: Phytosphingosine Stimulates the Differentiation of Human Keratinocytes and Inhibits TPA-Induced Inflammatory Epidermal Hyperplasia in Hairless Mouse Skin

Figure 6

Inhibition of TPA-induced PGE2 synthesis by phytosphingosine. Mouse peripheral mononuclear leukocytes were treated with TPA (16 nM) and indomethacin (1 nM and 10 nM), phytosphingosine (PS, 5 µM), or troglitazone (TGZ, 5 µM) for 16 h. PGE2 released into culture media was analyzed by enzyme immunoassay. Data represent the mean ± SD of 3 independent experiments. *Significant at P < 0.05. **Significant at P < 0.01.

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Molecular Medicine

ISSN: 1528-3658