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Figure 9 | Molecular Medicine

Figure 9

From: Predifferentiated Embryonic Stem Cells Prevent Chronic Pain Behaviors and Restore Sensory Function Following Spinal Cord Injury in Mice

Figure 9

Immunohistochemical staining 60 days after media injection (A, C) and ES cell transplantation (B, D). (A) Visualization of NeuN-positive cells in media-injected spinal cord. Arrows indicate neuronal loss in all laminae ipsilateral to injury. (B) Visualization of NeuN-positive cells in ES cell-transplanted spinal cord. Arrows indicate side ipsilateral to injury. Note increased number of immunostained neuronal cells. (C) Visualization of GFAP-positive cells in media-injected spinal cord. Arrows indicate areas of high staining intensity in side ipsilateral to injury. (D) Visualization of GFAP-positive cells in ES cell-transplanted spinal cord. Arrows indicate increased intensity of GFAP staining in only a small area on side ipsilateral to injury and cell transplant.

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