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Figure 1 | Molecular Medicine

Figure 1

From: Differential Expression of Receptor Tyrosine Kinases (RTKs) and IGF-I Pathway Activation in Human Uterine Leiomyomas

Figure 1

Differential expression of phosphorylated growth factor RTKs in leiomyoma and myometrial tissues.

(A, B) Out of 17 RTKs analyzed in the Phosphorylation of Receptor Tyrosine Kinases Array, 15 growth factor RTKs were highly expressed (P < 0.02–0.03) in leiomyoma (L) tissue compared with myometrial (M) tissue. These RTKs belong to the EGF, FGF, IGF-I, HGF, and PDGF growth factor receptor gene families. The array was done on pooled samples of ten leiomyoma tissue lysates and ten patient-matched myometrial tissue lysates from ten patients, and the dot and triangle symbols represent the dot blot (n = 4) intensity values for pooled myometrial and leiomyoma samples, respectively.

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Molecular Medicine

ISSN: 1528-3658