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Figure 3 | Molecular Medicine

Figure 3

From: Upregulated ATM Gene Expression and Activated DNA Crosslink-Induced Damage Response Checkpoint in Fanconi Anemia: Implications for Carcinogenesis

Figure 3

Kinetics of IR-induced and MMC-induced γ-H2AX foci in FANCA-mutant primary fibroblast cells compared with gene-corrected controls. (A) Kinetics and time course of cells scored positive for γ-H2AX foci up to 48 h after irradiation. (B) Kinetics and time course of cells scored positive for γ-H2AX foci up to 48 h after MMC washout. Diamond, GM1309C; square, gene-corrected control. Error bars represent SEM.

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Molecular Medicine

ISSN: 1528-3658