Genome-Wide Association Study of Determinants of Anti-Cyclic Citrullinated Peptide Antibody Titer in Adults with Rheumatoid Arthritis

Table 5 Association between HLA-DRB1 alleles and anti-CCP titer, and LD with the most strongly associated SNP

DRB1 allele	Association with anti-CCP, P value	LD with SNP rs1041885 (R²)
DR1	0.3531	0.0296
DR2	0.1025	0.0019
DR3	0.0003	0.4621
DR4	4 × 10⁻⁷	0.0935
DR7	0.5409	0.0119
DR11_DR13	0.0184	0.0353
	2 × 10⁻⁷	0.1447

ISSN: 1528-3658