Figure 3
rAAV-CD151 transfection enhances myocardial perfusion and reduces ischemia. (A) 13N-NH3 PET images of the control group. (B-D) 13N-NH3 PET images of the rAAV-GFP rAAV-CD151, and rAAV-antiCD151 groups in three axes. (B) Short axis images. (C) Vertical axis images. (D) Horizontal axis images. The control group exhibited no detectable defect. At 3 d after viral transduction, three viral transduced groups displayed similar myocardial perfusion. At 8 wks after viral administration, the rAAV-CD151 group exhibited significantly improved myocardial perfusion compared with the rAAV-GFP group. In contrast, rAAV-antiCD151 group revealed decreased perfusion.