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Figure 4 | Molecular Medicine

Figure 4

From: CD151 Gene Delivery after Myocardial Infarction Promotes Functional Neovascularization and Activates FAK Signaling

Figure 4

CD151 gene delivery improves myocardial function. (A) and (B) LVEF% and LVFS% showed myocardial contractile function was improved in the rAAV-CD151 group, but decreased in the rAAV-antiCD151 group 8 wks after vector administration. LVEF, left ventricular ejection fraction; LVFS, left ventricular shortening fraction. (C) and (D) ΔALWT% and ΔIVST% showed the regional motion of anterior lateral and interventricular septal wall was improved in the rAAV-CD151 group 8 wks after vector administration. ΔALWT, anterior lateral wall systolic thickening fraction; AIVST, interventricular septal systolic thickening fraction. (E) and (F) ALWTd and IVSTd showed the thickness of anterior lateral and interventricular septal wall was increased in the rAAV-CD151 group 8 wks after vector administration. ALWTd, anterior lateral wall diastolic thickness; IVSTd, interventricular septal diastolic thickness. Data are presented as mean ± SEM (n = ∼4–6 per group). &P < 0.05 versus control group; *P < 0.05 versus control and rAAV-GFP groups; **P < 0.05 versus rAAV-GFP group.

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