Upregulation of SPRR3 Promotes Colorectal Tumorigenesis

Table 1 Baseline demographic and biological features of 128 colorectal cancer patients.

Features	No. of patients (missing values)
Sex, male/female	64/64
Age, years, mean ± SD	59 ± 12
Stage,^a I/II/III/IV	11/42/55/20
Preoperative serum carcinoembryonic antigen, ≤6/>6 ng/mL Tumor characteristics	89/39
Site,^b right colon/left colon/rectum	25/41/62
Long diameter, ≤4/>4 cm	38/90
Growth pattern, expanding/infiltrative	109/19
Differentiation, well and moderately differentiated/poorly differentiated and mucinous	115/13
Lymphovascular invasion, no/yes	67/61
Either MLH1 or MSH2 expression, no/yes	9/84 (35)

^aCancer staging according to the American Joint Committee on Cancer (sixth edition, 2001; http://www.cancerstaging.org).
^bRight colon, cecum-splenic flexure of the transverse colon; left colon, splenic flexure of the transverse colon-sigmoid colon.

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