Table 2 Anthropometric and biochemical variables in the morbidly obese patients, classified according to their HOMA-IR, and the controls.

n (men/women)

11 (3/8)

22 (6/16)

18 (6/12)

Age (years)

49.2 ± 15.4

43.6 ± 13.4

41.0 ± 8.8

Weight (kg)

77.0 ± 13.0

145.2 ± 30.8^a

158.8 ± 24.8^a

BMI (kg/m²)

27.5 ± 2.1

54.5 ± 7.3^a

56.1 ± 5.9^a

Waist (cm)

84.8 ± 8.7

139.4 ± 20.6^a

150.6 ± 19.5^a

Hip (cm)

103.2 ± 7.4

154.9 ± 18.7^a

157.5 ± 13.1^a

Waist-to-hip ratio

0.88 ± 0.08

0.89 ± 0.06

0.95 ± 0.11

Glucose (mmol/L)

6.04 ± 0.60

5.47 ± 0.53

5.82 ± 0.65

Cholesterol (mmol/L)

4.87 ± 0.86

5.28 ± 1.08

4.86 ± 0.72

Triglycerides (mmol/L)

0.90 ± 0.41

1.28 ± 0.47

1.38 ± 0.85

Free fatty acids (mmol/L)

0.315 ± 0.030

0.739 ± 0.320^a

0.659 ± 0.234^a

Insulin (pmol/L)

76.7 ± 31.8

115.8 ± 28.2

280.9 ± 88.3^a,b

HOMA-IR

3.14 ± 1.43

3.90 ± 1.00

9.90 ± 2.90^a,b

Aspartate aminotransferase (U/L)

20.7 ± 8.3

20.1 ± 7.2

22.1 ± 7.6

Alanine aminotransferase (U/L)

42.2 ± 13.5

34.9 ± 12.0

48.2 ± 18.8^b

γ-Glutamyltransferase (U/L)

32.2 ± 17.0

54.5 ± 77.2

73.9 ± 110.0^a

Leptin (ng/mL)

10.0 ± 3.4

185.9 ± 97.6^a

189.7 ± 70.7^a

Adiponectin (ng/mL)

19.7 ± 8.27

11.0 ± 4.4^a

8.2 ± 4.17^a,b