Table 1 General characteristics of experimental groups^a

Plasma glucose (mmol/L)

3.7 ± 0.2

21.7 ± 1.5^b

16.1 ± 3.1^b,c

18.2 ± 1.3^b,c

Hb A_1c(% of Hb)

5.7 ± 0.3

8.8 ± 0.6^b

7.2 ± 0.5^c

6.8 ± 0.5^c

Body weight (g)

448 ± 25

270 ± 21^b

316 ± 15^b

273 ± 17^b

Heart weight (g)

1.17 ± 0.08

0.86 ± 0.05^b

0.90 ± 0.05^b

0.81 ± 0.04^b

Heart weight/body weight (mg/g)

2.62 ± 0.10

3.25 ± 0.15^b

2.86 ± 0.08

3.02 ± 0.16