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Table 1 Plasma and tissue markers of oxidative stress in experimental groupsa

From: Inhibition of Aldehyde Dehydrogenase 2 by Oxidative Stress Is Associated with Cardiac Dysfunction in Diabetic Rats

Parameter

Control (n = 8)

Diabetic (n = 8)

Diabetic + NAC treatment (n = 6)

Diabetic + α-LA treatment (n = 6)

Total antioxidant concentration (mmol/L)

1.40 ± 0.20

0.73 ± 0.09b

1.18 ± 0.09c

1.16 ± 0.08c

Mn-SOD (U/mg prot)

64.53 ± 1.82

55.81 ± 2.71b

64.31 ± 2.70c

61.58 ± 2.41c

GSH (mg/g prot)

5.08 ± 0.28

3.40 ± 0.15b

4.40 ± 0.26c

4.12 ± 0.22b,c

MDA (nmol/mg prot)

2.10 ± 0.21

2.96 ± 0.27b

2.20 ± 0.10c

2.31 ± 0.17c

  1. aData are presented as mean ± SEM.
  2. bP < 0.05 versus control group.
  3. cP < 0.05 versus diabetic group.
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Molecular Medicine

ISSN: 1528-3658