Table 3 Genotype and allele frequencies of the CYP1A1*1 and *4 in patients with PCT and controls in this study and in a previous study in Germany.
From: CYP1A2*1F and GSTM1 Alleles Are Associated with Susceptibility to Porphyria Cutanea Tarda
| Â | Â | Â | Genotype frequency | Allele frequency | |||
|---|---|---|---|---|---|---|---|
Study | PCT subtype | n | *1/*1,% | *1/*4, % | *4/*4, % | *1, % | *4, % |
This study (USA) | PCT 1 & 2 | 71 | 97.2 | 2.8 | 0.0 | 98.6 | 1.4 |
| Â | PCT 1 | 53 | 96.0 | 4.0 | 0.0 | 98.0 | 2.0 |
| Â | PCT 2 | 16 | 100.0 | 0.0 | 0.0 | 100.0 | 0.0 |
| Â | Controls | 70 | 91.4 | 8.6 | 0.0 | 95.7 | 4.3 |
Gardlo et al. (Germany) (29) | PCT 1 & 2 | 46 | 82.6 | 17.4 | 0.0 | 85.3 | 14.7 |
| Â | PCT 1 | 29 | 89.7 | 10.3 | 0.0 | 94.8 | 5.2 |
| Â | PCT 2 | 17 | 70.6 | 29.4 | 0.0 | 85.3 | 14.7 |
| Â | Controls | 101 | 92.6 | 7.4 | 0.0 | 100.0 | 0.0 |