Figure 3
From: Differential Roles of Estrogen Receptors α and β in Control of B-Cell Maturation and Selection
BAFF mRNA levels in splenocytes of WT, ERα-deficient and ERβ-deficient mice. Total splenocyte RNA from spleens of mice treated with E2 pellets for 6 wk was used to measure BAFF levels. BAFF was increased after administration of E2 compared with placebo in WT, ERα-deficient and ERβ-deficient mice (n = 5 per group). Student t test was used to analyze the significance between the groups.