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Figure 1 | Molecular Medicine

Figure 1

From: Expression of a Broad Array of Negative Costimulatory Molecules and Blimp-1 in T Cells following Priming by HIV-1 Pulsed Dendritic Cells

Figure 1

HIV-pulsed DCs impair T-cell proliferation. Mature DCs were pulsed with HIV (750 ng/mL) for 24 h, washed and cocultured with CFSE-labeled naïve bulk T cells at a ratio of 1:10 (DC:T cells). Assays were restimulated after 7 d and T-cell proliferation was measured after 24 h (d 8) by flow cytometry. (A) Mock- and HIV-pulsed DCs cocultured with naïve T cells (a representative of one experiment). (B) Ten combined experiments normalized together (P < 0.001).

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Molecular Medicine

ISSN: 1528-3658