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Figure 2 | Molecular Medicine

Figure 2

From: Attenuation of Endoplasmic Reticulum Stress-Related Myocardial Apoptosis by SERCA2a Gene Delivery in Ischemic Heart Disease

Figure 2

Restoration of SERCA2a expression attenuates myocardial apoptosis and reverses the increase of GRP78. (A) TUNEL staining of apoptotic myocardial cells (pointed by the arrows). (B) Immunohistochemical staining of GRP78 protein. The GRP78 proteins are stained in brown. (C) Quantitative analysis of TUNEL-positive cells. (D) Quantitative analysis of GRP78 density. Data are presented as mean ± SEM (n = 4∼6 per group). IOD, integrated optical density.

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