Table 2 The effect of infliximab or placebo on acute phase proteins and vessel wall parameters (mean ± SEM)

hsCRP (µg/L)

2.8 ± 0.6

1.8 ± 0.5

−1.0 ± 0.18

0.02

1.5 ± 0.9

2.0 ± 0.5

0.6 ± 0.4

ns^b

Fibrinogen (g/L)

3.42 ± 0.18

3.18 ± 0.28

−0.26 ± 0.15

0.037

3.37 ± 0.26

3.83 ± 0.14

−0.47 ± 0.20

ns

FMD^c (%)

6.4 ± 1.5

4.9 ± 0.4

−1.5 ± 1.8

ns

6.6 ± 0.5

4.9 ± 1.2

−1.7 ± 1.5

ns

NMD^d (%)

13.6 ± 2.5

13.4 ± 1.5

−0.2 ± 1.6

ns

15.8 ± 3.4

16.4 ± 3.7

0.7 ± 3.3

ns

sICAM-1 (µg/L)

40 ± 3

41 ± 4

1 ± 1.3

ns

39 ± 7

30 ± 6

−3 ± 2

ns

vWF (%)

139 ± 30

134 ± 5

7 ± 21

ns

99 ± 9

66 ± 8

33 ± 11

ns

PAI-1 (µg/L)

54 ± 10

55 ± 14

1 ± 7

ns

48 ± 8

53 ± 16

4 ± 8

ns