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Table 3 Neonatal blood gasometric evaluation 5 min after birth.a

From: Local Fetal Lung Renin-Angiotensin System as a Target to Treat Congenital Diaphragmatic Hernia

 

pH

PCO2 (mmHg)

PO2 (mmHg)

SatO2 (%)

Lactate (mmol/L)

C + S

7.30 ± 0.03

22.69 ± 2.33

102.80 ± 7.78

93.60 ± 2.50

6.83 ± 0.39

N + S

6.94 ± 0.03b

38.49 ± 3.21b

62.50 ± 5.36b

67.25 ± 5.58b

8.50 ± 0.51b

CDH + S

6.92 ± 0.02b

51.05 ± 1.71bc

52.00 ± 6.06b

58.50 ± 7.06b

9.56 ± 0.57b

N + PD

7.18 ± 0.08c

23.62 ± 3.39c

95.67 ± 6.49c

90.83 ± 2.44c

6.88 ± 0.82c

CDH + PD

7.03 ± 0.04de

24.63 ± 5.83d

95.00 ± 8.20d

87.80 ± 3.65d

6.73 ± 0.70d

  1. C, control; CDH, congenital diaphragmatic hernia; N, nitrofen; PD, PD-123319; PCO2,CO2 partial pressure; PO2, O2 partial pressure; S, saline; SatO2, O2 saturation.
  2. aValues represent the mean ± SEM of measurements.
  3. bP < 0.05 versus C + S; cversus N + S; dversus CDH + S; eversus N + PD. There is a statistically significant interaction between variables: disease-treatment for pH, PCO2, PO2 and SatO2.