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Figure 2 | Molecular Medicine

Figure 2

From: Oxidized Low-Density Lipoprotein-Dependent Platelet-Derived Microvesicles Trigger Procoagulant Effects and Amplify Oxidative Stress

Figure 2

CD36-dependent platelet activation in response to PMVs. (A–C) The MFI and percentage of PAC-1, as well as platelet aggregation, were enhanced significantly after incubation of CD36-positive platelets with PMVs (30 µg/mL) for 30 min at 22°C. Data are means ± SE (n = 3). *P < 0.05 compared with control. (D–F) PAC-1 expression or platelet aggregation with CD36-deficient platelet incubation in response to PMVs. Data are means ± SE (n = 4). *P < 0.05 compared with control.

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