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Figure 2 | Molecular Medicine

Figure 2

From: Constitutive Overexpression of the Oncogene Racl in the Airway of Recurrent Respiratory Papillomatosis Patients Is a Targetable Host-Susceptibility Factor

Figure 2

The Rac1 →COX-2 pathway is activated in clinically normal tissues of RRP patients. A representative Western blot of COX-2 levels in laryngeal tissue from a non-RRP patient (N) and papilloma (P) and clinically normal laryngeal (CNL) and tracheal (CNT) tissues from a RRP patient is shown. Actin is shown as a loading control. The graph shows mean ± SD of tissues from four different RRP patients compared with normal tissue from a non-RRP patient (N). Previous publication showed the statistical difference between true normal and papilloma tissues (3). There was no statistically significant difference between COX-2 expression in papillomas and clinically normal tissues of RRP patients.

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