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Figure 5 | Molecular Medicine

Figure 5

From: The Infective Polymerization of Conformationally Unstable Antithrombin Mutants May Play a Role in the Clinical Severity of Antithrombin Deficiency

Figure 5

Intracellular antithrombin in HEKEBNA cells transfected with conformational unstable mutants under moderate stress. Cells were transfected with WT plasmid alone (WT/-) or in combination with Δ393 (WT/L), F239S (WT/F) and M338T (WT/mol/L). Cell lysates after treatment for 5 h at pH 6.5 were run in SDS-PAGE under reducing (A) and nonreducing conditions (B) and antithrombin was detected by Western blottng. β-Actin was used as loading control.

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Molecular Medicine

ISSN: 1528-3658