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Figure 1 | Molecular Medicine

Figure 1

From: High Mobility Group Box 1 Contributes to the Pathogenesis of Experimental Pulmonary Hypertension via Activation of Toll-like Receptor 4

Figure 1

HMGB1 in human IPAH. (A) Localization of HMGB1 in lung sections of patients with and without IPAH by immunohistochemistry (brown = HMGB1, blue = hematoxylin, scale bar = 50 µm). (B) Circulating HMGB1 was measured in serum from IPAH patients (n = 21) or healthy controls (n = 15). Open circles show the levels of individual patients. The line and error bars show the mean and 95% confidence intervals. (C) Correlation of mean pulmonary artery pressure (mPAP) with circulating HMGB1 levels in IPAH patients (n = 16 patients). The r represents the Pearson correlation coefficient. Dashed lines represent the 95% confidence intervals.

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Molecular Medicine

ISSN: 1528-3658