Skip to main content
Figure 4 | Molecular Medicine

Figure 4

From: Adeno-associated Virus Serotype 8 (AAV8) Delivery of Recombinant A20 to Skeletal Muscle Reduces Pathological Activation of Nuclear Factor (NF)-κB in Muscle of mdx Mice

Figure 4

Electromobility shift assay of NF-κB activation in mdx quadriceps and diaphragm. (A) Nuclear extracts from quadriceps and diaphragm of C57 and mdx mice treated with AAV8-tMCK-A20 (AAV8-A20) or saline were assessed for NF-κB activity by using an EMSA. Results from three representative mice from each group are shown. (B) Quantification of NF-κB activation. Band intensities from each blot were measured and averaged for each group. *p < 0.05. n = 3 for C57 mice; n = 9 for saline-treated mdx mice; n = 12 for AAV8-tMCK-A20-treated mdx mice. A.U., arbitrary units.

Back to article page

Molecular Medicine

ISSN: 1528-3658