Figure 3
From: Signaling Pathways in Leiomyoma: Understanding Pathobiology and Implications for Therapy
Schematic presentation of transforming growth factor-β, activin, myostatin and Smad signaling in uterine leiomyoma. ↑ and ↓ denote increased (red) or decreased (blue) level or function, respectively. TGF-β: transforming growth factor-β; TβRI: transforming growth factor-β receptor I; TβRII: transforming growth factor-β receptor II; ALK4: activin-like kinase-4 (activin receptor type-1B); ActRII: activin receptor type II.